I used two center speakers for a home theatre room, AND for an audio room (I have two setups). The only thing needed is to compensate for the higher volume from two centers, by lowering the levels in setup....

If you use the autosetup, that will take care of adjusting the proper levels.

BTW, I drive each of the centers with its own amp channel, just as with any of the other speakers in my 7.1 setup.

Hope this helps....