Normally I would not think of electronic equipment, which does have any moving parts, as being subject to vibration but.. transformers are known to hum sometimes. It could be a loose mounting screw or an isolator that is not performing well. The transformers in these amps are very large and need to serious mounting hardware so it is possible that is the issue. Once you get the cover off and do your inspection, if you don't find the issue, I would plug it in and let it sit until the noise starts and see if you can physically locate it. Obviously this will require some care on your part but if it finds the issue then you have a chance to fix it. If the transformer is humming you should be able to easily find it just by touching the external insulated portion and feeling the vibration. Pushing on them a little might cause the hum to change if it is a mounting issue. If it not the transformers then touch the heat sinks on each channel and lightly push them a little to see if the hum changes. Good luck and be careful.
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Music system
Model 990/7500/Magnepan 1.6 QRs/Technics SL1200 MK2/Aperion S-12 Subwoofer/OWA3/Sony NS75H DVD
APC H15 Power Conditioner

TV System
Large Advent Loudspeakers/ Polk center/Monoprice surrounds/Panasonic Viera 42 inch/Onkyo HT-RC260/Sony BDP S590/Directv


Home Theater System
Onkyo PR-SC886/Outlaw 7125 Klipsch RF-82 L/R,RC-62 center, RB-35 SR/SL, BENQ HT1075, Outlaw LFM1-EX/OPPO BDP-83/Directv
Harmony ONE
Blue Jeans and Monoprice interconnects
APC H15 Power Conditioner