Makes the first round of EQ pointless, because you're EQing each sub under conditions it will never ever be heard in (i.e., by itself). That's like manually EQing the sub flat with the door open, and then closing the door and letting Audyssey EQ it again under the conditions it will actually be heard in. Heck, you don't even know whether some of the settings in the first round of EQing are making things more difficult for the second round.