I think Axiom is an impressive brand, and if the M3ti is any indication they are easily comparable to Paradigm's Monitor series - the bigger speakers (M60 and M80) may even top the Monitor line. As with Paradigm, of course, you first need to be someone who likes the particular character of a Canadian speaker design.

I haven't heard the Signatures - I don't know if my Paradigm dealer even has any in the showroom (their big Paradigm demo has historically been a set of Studio/100's in a two-channel setup, although I did get them to set up a Studio/60 demo for me when I bought mine a few years back). They look really impressive.