Whether it is the crossover or the "distance"/timing settings, I would not generally alter/filter/process the signal of any individual channel more than once.

If you are using the analog bypass inputs on the 950, then you may adjust “distance”/timing prior to the inputs. If you are using an input on the 950 that properly adjusts for “distance”/timing within the 950, then the signals should arrive at the 950 without variance in “distance”/timing. If the “distance”/timing on a channel is modified twice in the same signal path, the “distance”/timing will be the sum of the two settings in a single path.

Similarly for crossovers, the best choice is to filter once per signal path. Filtering the same signal path twice at the same frequency will give you a more aggressive roll-off rate. This may cause a “dip” in the response curve at the crossover frequency, perhaps making the blending of loudspeaker and subwoofer components more difficult, and should be avoided unless a very fast roll-off is needed for a special reason. If the same signal goes through two filtering stages at different frequencies, then one would see an uneven roll-off graph with changes in the rate at each frequency. Again, this is something one generally avoids unless there are special circumstances where this would be helpful.

Hope this helps.