scribner,

I don't have the background to compare RG59 to RG6 but when I had a in-wall coax custom made for a subwoofer (before I learned how to make my own) by a local electronics company they used RG59. The run with all the bends is about 20' and I've not had any problems. I'm sure RG6 would work too. I would use a quality cable from Canare or Belden (versus generic cable from Home Depot) and good connectors from Canare or Steren. I recall an ealier post that used RG6 terminated with an F connector and then a F to RCA adapter was used to connect a sub. Hope this helps.