It would be cool and maybe we should invent it!! The hardware likely exists and you could use any Pre/Pro to drive it. It is just a matter of setting up a few routers to accept the output of the various players and other input devices and feeding them to the Pre/Pro so it can output to another router to send to whatever speaker amps are setup with their routers. It sounds hard, but the first one to invent a high quality combo amp/router will clean up. You could position the router amps where you wanted them and they would output to the speakers using lamp cord. You could put them in a coffee table or in end tables. C'mon guys tell me someone hasn't already invented this.
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Music system
Model 990/7500/Magnepan 1.6 QRs/Technics SL1200 MK2/Aperion S-12 Subwoofer/OWA3/Sony NS75H DVD
APC H15 Power Conditioner

TV System
Large Advent Loudspeakers/ Polk center/Monoprice surrounds/Panasonic Viera 42 inch/Onkyo HT-RC260/Sony BDP S590/Directv


Home Theater System
Onkyo PR-SC886/Outlaw 7125 Klipsch RF-82 L/R,RC-62 center, RB-35 SR/SL, BENQ HT1075, Outlaw LFM1-EX/OPPO BDP-83/Directv
Harmony ONE
Blue Jeans and Monoprice interconnects
APC H15 Power Conditioner