I had mine hooked up in a 4.1 setup for quite a while, but used it primarily for 2 channel analog audio with both a 7075 and a 7125. I was very pleased with its performance. In fact, at this price I'm thinking about getting another one!
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HT:
Pioneer VSX-1120
Salk Songbirds, SongCenter, SongSurrounds
Panasonic BDP-45
Outlaw LFM-2

2 Channel:
Red Dragon M-500 monoblocks
BAT-VK3i
Salk HT-1TL's
Apple TV
Beresford 7520 DAC
Surgex XS10