Set the crossovers on the 990 - the settings on your sub will only affect the subwoofer itself, and it's best to either disable the sub's crossover or set it as high as it allows.
Unless you have absolute monster speakers, you'll want to set all of them to small - tower or bookshelf. You can tell the 990 what crossover to use based on the response range of your specific speakers.
This thread may help you decide how to set the crossovers.