Pizzapro:
Agree with all above. Setup can also mean speaker placement from rear walls and side walls, toe-in. What is opposite where your tweeters are facing? A window? Open wall?
I've got Axiom M80ti's and those are comparable to Paradigms definitely. I don't find them harsh and fatiguing at all. I've got my 990 mated to a Sherbourn 5/1500A and it's more power than I probably need. Even in two channel listening, I still cross over to dual SVS's - I don't run the mains as full ever; just my preference.
What kind of amp are you running with the 990? Did you keep the 1075 - if your speakers are set to large, you can add to the treble fatigue potentially if your amp is not up to snuff because so much of the power goes to drive the bass.