It will depend upon the impedance of the speakers and the ability of the amps! If you are running a Krell with 8 ohm speakers you would have no problem. Keep in mind that speaker impedance varies with frequency! The best (safest) bet would be to run two identical amps, each running identical center channels. Best sonic balance would be achieved using one amp. The one amp approach would be better if the amp was a vacuum tube type (not as much concern for low impedance)!!! Be sure to set for 2 ohms, though!!!