In general you'll get a better laid out system if you go pre/pro or receiver centric rather than TV centric.

So think of the 1050 as the hub of your HT system and everything else is either a signal source or an output device. If you use OTA and need the TV built in tuner it will complicate things a bit, but if your set top box has AV out there's no need to switch channels on the TV again, plus you may get better quality video by skipping the RF modulator stage on the STB.

I would run a coax to the VCR (but no further) from the cable box simply so it can record OTA if you want it without involving the STB tuner. Then connect The VCR In/Out to the 1050 along with all the source outputs, hook up speakers, use the 'TV' as a video monitor (from the 1050) and you should be set.

YMMV.