I would think you will want larger speakers eventually to fill that size room. Especially for HT applications. I am struggling with a similar issue and have gone with a larger amp and likely will go with Axiom M80s or Aperion 633Ts for the other house. I did consider some Magnepan 1.6s but they are inefficient and I wanted to go with a 5.1 setup. I have heard them before and they are fabulous speakers for music and great for HT if setup right. Try to set you room up as symetrically as possible taking into account walls and floor reverberation effects. My house up north has a great room with 25' ceiling peaked in the center and occupies a huge volume because it is connected to a loft and foyer and kitchen area. I am holding out for the 997 for the Trinnov in hopes that it will help out with the reverberation. A lot can be gleaned from the various online HT mags and AVSforum but until its actually making noise I won't be able to tell what I need to do.
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Music system
Model 990/7500/Magnepan 1.6 QRs/Technics SL1200 MK2/Aperion S-12 Subwoofer/OWA3/Sony NS75H DVD
APC H15 Power Conditioner
TV System
Large Advent Loudspeakers/ Polk center/Monoprice surrounds/Panasonic Viera 42 inch/Onkyo HT-RC260/Sony BDP S590/Directv
Home Theater System
Onkyo PR-SC886/Outlaw 7125 Klipsch RF-82 L/R,RC-62 center, RB-35 SR/SL, BENQ HT1075, Outlaw LFM1-EX/OPPO BDP-83/Directv
Harmony ONE
Blue Jeans and Monoprice interconnects
APC H15 Power Conditioner