I programmed mine in about 30 minutes after I got all the model numbers for the machines. It also let me manually set it up to use my MP3 player through the 990 audio 5. All I have to do is turn the MP3 player on and hit one button on the Harmony and Viola! it works perfect. It sometimes loses it mind but it has a help button that fixes whatever the problem is every time. I think most of the issues are not keeping it directed at the HT for long enough to let it get the signals through. I also programmed it to let me use a utility function to pull up my (() menu on screen without me have to switch the TV input and hit the menu button. It also has a sensor that detects when it is being moved and turns it on so when you grab it, its ready to go. Just for the wifes sake I will always have one of these. I would also imagine that you could program it for multiple HT or stereo setups so you only need on remote for all your equipment.